Amidohydro_1: Amidohydrolase family
| PAG Title | Amidohydro_1: Amidohydrolase family |
| PAG ID | PEX001836 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | This family of enzymes are a a large metal dependent hydrolase superfamily 1. The family includes Adenine deaminase EC:3.5.4.2 that hydrolyses adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source 2. This family also includes dihydroorotase and N-acetylglucosamine-6-phosphate deacetylases, EC:3.5.1.25 These enzymes catalyse the reaction N-acetyl-D-glucosamine 6-phosphate + H2O <=> D-glucosamine 6-phosphate + acetate. This family includes the catalytic domain of urease alpha subunit 3. Dihydroorotases (EC:3.5.2.3) are also included 4-5. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 0 |
| Information Content | Poor |
| Other IDs | PF01979 |
| Base PAG ID | PEX001836 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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